Walking-related knee contact forces and associations with knee pain across people with mild, moderate and severe radiographic knee osteoarthritis: a cross-sectional study

W Wu; AL Bryant; RS Hinman; KL Bennell; BR Metcalf; M Hall; PK Campbell; KL Paterson

Journal article

Walking-related knee contact forces and associations with knee pain across people with mild, moderate and severe radiographic knee osteoarthritis: a cross-sectional study

W Wu, AL Bryant, RS Hinman, KL Bennell, BR Metcalf, M Hall, PK Campbell, KL Paterson

Osteoarthritis and Cartilage | Published : 2022

DOI: 10.1016/j.joca.2022.02.619

Abstract

Objective: To investigate knee contact forces (KCFs), and their relationships with knee pain, across grades of radiographic knee osteoarthritis (OA) severity. Design: Cross-sectional exploratory analysis of 164 participants with medial knee OA. Radiographic severity was classified as mild (grade 2), moderate (grade 3) or severe (grade 4) using the Kellgren & Lawrence (KL) scale. Walking knee pain was assessed using an 11-point numerical rating scale. External knee adduction moment (external KAM) and internal muscle forces were used to calculate medial, lateral and total KCFs using a musculoskeletal computational model. Force-time series across stance phase of gait were compared across KL gra..

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The trial was funded by the Australian National Health and Medical Research Council (Project #1044396) . KLP is supported by a National Health & Medical Research Council Emerging Leadership Investigator Grant (#1174229) . RSH is supported by a National Health & Medical Research Council Senior Research Fellowship (#1154217) . KLB is supported by a National Health & Medical Research Council Leadership Investigator Grant (#1174431) . MH is supported by a National Health & Medical Research Council Emerging Leadership Investigator Grant (#1172928) . The study sponsors had no role in the study design, collection, analysis and interpretation of data; in the writing of the manuscript; or in the decision to submit the manuscript for publication.